| 2.33 | Post-marketing reporting of adverse drug reactions to human medicines in South Africa | October 27, 2021 | 9 | PHARMACOVIGILANCE | Download PDF |
| 5.08 | Reliance Guideline | October 13, 2021 | 2 | GENERAL, ECTD & HUMAN MEDICINES GUIDELINES | Download PDF |
| 2.11 | Safety Reporting During Clinical Trials | October 12, 2021 | 4 | CLINICAL TRIALS | Download PDF |
| 9.129 | Re-submission of BAU New Medicines Applications from 2018 and 2019 | October 5, 2021 | 1 | ORTHODOX MEDICINES | Download PDF |
| 2.66 | Guideline for Lot release of human vaccines | October 4, 2021 | 1 | ORTHODOX MEDICINES | Download PDF |
| 5.09 | GUIDELINE ON HOW TO LODGE A COMPLAINT ON MEDICINES AND MEDICAL DEVICES | October 4, 2021 | 2 | REGULATORY COMPLIANCE | Download PDF |
| 8.05 | CLASSIFICATION of MEDICAL DEVICES and IVDs | September 10, 2021 | 5 | MEDICAL DEVICES | Download PDF |
| 2.64 | Availability of medicines for use in a public health emergency | August 25, 2021 | 1 | GENERAL, ECTD & HUMAN MEDICINES GUIDELINES | Download PDF |
| 2.52 | Section 21 Access to Unregistered Medicines | August 25, 2021 | 3 | UNREGISTERED PRODUCTS | Download PDF |
| 2.04 | Post importation testing guideline | August 23, 2021 | 4 | INSPECTORATE & REGULATORY COMPLIANCE | Download PDF |
