Fluoropyrimidine containing medicines and related substances: Increased drug exposure and toxicity in patients with dihydropyrimidine dehydrogenase (DPD) deficiency

Fluoropyrimidine containing medicines and related substances: Increased drug exposure and toxicity in patients with dihydropyrimidine dehydrogenase (DPD) deficiency

In collaboration with the South African Health Products Regulatory Authority (SAHPRA), the companies listed below would like to inform you of the requirement of pre-testing to identify patients at increased risk of severe toxicity due to fluoropyrimidine containing medicines.

2020 Oct

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File Type: pdf
Category: Communication To Health Care Professionals
Unit: pharmacovigilance