Guideline for Destruction of Medicines and Scheduled Substances

This document provides guidance regarding safe disposal and destruction of medicines and scheduled substances by health facilities in accordance with Regulation 44 of the General Regulations of the Medicines and Related Substances Act, 101 of 1965, and relevant waste legislation. To ensure the correct handling of the disposal and destruction of medicines and scheduled substances.

The General Regulations of the Medicines and Related Substances Act (Act 101 of 1965) gazetted on 25 August 2017, replaced regulation 27 (destruction of medicines) with regulation 44 (destruction of medicines or scheduled substances). The Authority reserves the right to request any additional information to establish the safe destruction of any Scheduled medicines and/ or substances in South Africa.